Talk:Pancuronium bromide

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Untitled[edit]

I think that this should be moved to pancuronium since that would seem to conform to the norm. Any objections? Matt 04:29, 23 Jun 2004 (UTC)

"Recreational use" of a curaremimetic?![edit]

"Recreational use

Because of its unique paralytic properties, it has become popular in Eastern European countries, where it is manufactured illegally and used in private fetish clubs."

This sounds so unbelievable (let alone the 'illegal manufacture', since the manufacture of this compound poses a challenging task even for a skilled organic chemist with good equiped synthesis laboratory), that I suggest to delete it, unless someone provides a relevant source of this information. I can't imagine, how some fetishists would counteract the problem of respiratory paralysis in curarised person.--84.163.118.13 00:58, 11 October 2006 (UTC)[reply]


agreed - remove 202.36.134.22 02:22, 14 October 2006 (UTC)[reply]
Also agreed. Removed. Fvasconcellos 15:11, 14 October 2006 (UTC)[reply]

Mode of action[edit]

The molecular mode of action of this drug would be of value to this article if a pharmacologist knows it 202.36.134.22 02:23, 14 October 2006 (UTC)[reply]

ok, I'll try, though I'm not a pharmacologist (yet toxicology student:)--Spiperon 17:47, 14 October 2006 (UTC)[reply]


The CAS Number is for the bromide but the structure doesn't have the bromide counterions.--ChemSpiderMan (talk) 01:32, 20 December 2007 (UTC)[reply]

Drugbox[edit]

Seem to be some inconsistencies. Article title and pubchem ID is for a bis-quat ammonium ion. Structure is similarly for the ion. However, the CAS number listed is for the bromide (hyperlink broken). The lede mentions the bromide salt as well. The molecular mass entry would be inappropriate because it is not really a molecule. Though that is probably a limitation of drugbox.

What should we do? Move to pancuronium bromide? I didn't see any others mentioned in the article, but if there are, other salts can be mentioned and redirected here. --Rifleman 82 (talk) 20:11, 6 May 2008 (UTC)[reply]

In general, I have recommended locating drug articles at the parent compound of the active ingredient, with mention of any salt forms in the article text (and redirects from salt forms where necessary). With this one, I think we can make the title, text, and infobox data consistent for pancuronium cation. Particular salt forms, such as the bromide, can then be mentioned in the text and PubChem links to bromide salt can be put in external links. Most important to me is consistency, though. -- Ed (Edgar181) 19:01, 15 May 2008 (UTC)[reply]
I went ahead and made the article and infobox consistent for pancuronium, with mention of pancuronium bromide where appropriate. Feel free to revert if anyone objects. -- Ed (Edgar181) 19:19, 15 May 2008 (UTC)[reply]
This is not an ideal solution. The cation itself cannot have macroscopic physical properties, so we could have chembox for the bromide and drugbox for the cation. However, drugboxes are good for compounds with INNs, which is pancunorium bromide as well. ​​ —Mykhal (talk) 20:47, 22 July 2018 (UTC)[reply]
@Mykhal: Yeah, that was ten years ago - I don't think there was consensus about handling situations like this back then. I wouldn't do the same now. In the case of quaternary ammonium salts, INNs include the anion so we title the pages that way per WP:MOSPHARM - we should make the drugbox data consistent with title and INN. -- Ed (Edgar181) 21:46, 22 July 2018 (UTC)[reply]

New IUPAC Name[edit]

Suggested IUPAC Name is:

(2beta,3alpha,5alpha,16beta,17beta)-3,17-bis(acetyloxy)-2,16-bis(1-methylpiperidinium-1-yl)androstane —Preceding unsigned comment added by ChemSpiderMan (talk • contribs) 01:40, 21 May 2008 (UTC)[reply]

Suggested by whom? ​ —Mykhal (talk) 20:36, 22 July 2018 (UTC)[reply]

External links modified[edit]

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Cheers.—cyberbot IITalk to my owner:Online 22:30, 18 March 2016 (UTC)[reply]

The article is conflated with info for Pancuronium (PubChem 441289, molecular formula C35H60N2O4) - mostly in the info box, and its salt Pancuronium bromide (PubChem 27350, molecular formula C35H60Br2N2O4). The two aren't the same and can't share the same article. D00kSI (talk) 12:57, 14 July 2016 (UTC)[reply]

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