Talk:Mean corpuscular volume

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Worked Example[edit]

I would like to see the math because I just checked the worked example, and the MCV does NOT come out correctly if I include the factor of 10 as the formula suggests: 40% = 0.4; (0.4 x 10)/5e12 = 800e-15 = 800 fL (without the factor of 10, it would come out correctly).

Either the formula is wrong or the calculated example is wrong, or there is some piece missing. I suspect that the factor of 10 is just a rule of thumb used as a shortcut: 40/5 = 8; then multiply by 10 to get an MCV of 80 fL. Jdevola (talk) 19:08, 27 September 2012 (UTC)[reply]

I agree. I've spent way too long to figure out why there is a factor 10 but I found a source for it so I went ahead and change the formula. JuliusSimplus (talk) 10:51, 2 May 2020 (UTC)[reply]

I think I've worked it out. Hematocrit times sample volume gives the total volume of red blood cells, and dividing that by the number of red blood cells gives the mean corpuscular volume (WP:SYNthesising the definitions of Hct and MCV). Rearranging gives

{\text{Hct}}/({\text{number of red blood cells}}/{\text{sample volume}})

, or

{\text{Hct}}/[{\text{RBC}}]

. The factor of 10 comes from using Hct as a percentage (100) and cell concentration as millions per microlitre (

10^{12}

) and wanting an answer in femtolitres (

10^{-15}

).—dah31 (talk) 00:57, 25 February 2021 (UTC)[reply]

Elevated[edit]

Elevated MCV is associated with heavy alcohol use/abuse, NOT necessarily alcoholism. Niteowlneils 02:17, 17 Apr 2005 (UTC)

I removed this from the last line of text of the article "A mistake on line 7 Macrocytic Anemia is high MCV value" and figured it belonged here, rather than in the article Ruhrfisch 17:35, 26 April 2007 (UTC) Trebla67 (talk) 23:42, 30 June 2009 (UTC) I recommend endorsing the word "cell" as replacement for the archaic "corpuscular". Trebla67 (talk) 23:42, 30 June 2009 (UTC)[reply]

Measurement[edit]

Mean Corpuscular Volume can be obtained by detecting and measuring changes in electrical resistance when a red blood cel, diluted in a conductive liquid goes through a small aperture. Each cell suspended in a conductive liquid (diluent) acts as an insulator. As each cell goes through the aperture, it momentarily increases the resistance of the electrical path between two submerged electrodes, one located on each side of the aperture. This causes an electrical pulse that can be counted and sized. While the number of pulses indicates particle count, the size of the electrical pulse is proportional to the cell volume. —Preceding unsigned comment added by FBCBMS (talk • contribs) 11:47, 9 July 2010 (UTC)[reply]

infobox[edit]

infobox interventions should pull data from wikidata. This is linked on wikidata to a LOINC code.EncycloABC For example reference range could be displayed (also in wd) (talk) 19:08, 19 August 2019 (UTC)[reply]

A Question[edit]

Can the range of MCV vary based on age? — Preceding unsigned comment added by Abdul.Basit.Duke (talk • contribs) 08:48, 2 March 2023 (UTC)[reply]